Chronic subdural haematoma (CSDH) is an encapsulated collection of blood and fluid on
the surface of the brain. Historically considered a result of head trauma, recent evidence …

Chronic subdural haematoma (CSDH) is one of the most common neurological disorders,
and is especially prevalent among elderly individuals. Surgical evacuation is the mainstay of …

Decompressive craniectomy (DC)—a surgical procedure that involves removal of part of the
skull to accommodate brain swelling—has been used for many years in the management of …

Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
on postoperative recovery needs to be understood to inform clinical decision making during …

Background The effect of decompressive craniectomy on clinical outcomes in patients with
refractory traumatic intracranial hypertension remains unclear. Methods From 2004 through …

Background Chronic subdural haematoma causes serious morbidity and mortality. It recurs
after surgical evacuation in 5–30% of patients. Drains might reduce recurrence but are not …

A key aspect of nearly all single-cell sequencing experiments is dissociation of intact tissues
into single-cell suspensions. While many protocols have been optimized for optimal cell …

Objectives: We have sought to develop an automated methodology for the continuous
updating of optimal cerebral perfusion pressure (CPP opt) for patients after severe traumatic …

Objectives: To document the effect of neurocritical care, delivered by specialist staff and
based on protocol-driven therapy aimed at intracranial pressure (ICP) and cerebral …

Secondary insults can adversely influence outcome following severe traumatic brain injury.
Monitoring of cerebral extracellular chemistry with microdialysis has the potential for early …