Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis

K Bramham, B Parnell, C Nelson-Piercy, PT Seed… - Bmj, 2014 - bmj.com
Objective To provide an accurate assessment of complications of pregnancy in women with
chronic hypertension, including comparison with population pregnancy data (US) to inform …

The effect of smoking on COVID‐19 severity: A systematic review and meta‐analysis

RK Reddy, WN Charles, A Sklavounos… - Journal of medical …, 2021 - Wiley Online Library
Various comorbidities represent risk factors for severe coronavirus disease 2019 (COVID‐
19). The impact of smoking on COVID‐19 severity has been previously reported in several …

Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: systematic review and meta-analysis

E Oteng-Ntim, D Meeks, PT Seed… - Blood, The Journal …, 2015 - ashpublications.org
A systematic review and meta-analysis of observational studies were conducted to quantify
the association between sickle cell disease in pregnancy and adverse maternal and …

Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial

LC Chappell, PT Seed, AL Briley, FJ Kelly, R Lee… - The Lancet, 1999 - thelancet.com
Background Oxidative stress has been implicated in the pathophysiology of pre-eclampsia.
This randomised controlled trial investigated the effect of supplementation with vitamins C …

[HTML][HTML] Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial

L Poston, R Bell, H Croker, AC Flynn… - The lancet Diabetes & …, 2015 - thelancet.com
Background Behavioural interventions might improve clinical outcomes in pregnant women
who are obese. We aimed to investigate whether a complex intervention addressing diet …

[PDF][PDF] Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population‐based case‐control study

V Geenes, LC Chappell, PT Seed, PJ Steer… - …, 2014 - Wiley Online Library
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy‐specific liver disease,
characterized by maternal pruritus and raised serum bile acids. Our objectives were to …

Diagnostic accuracy of placental growth factor in women with suspected preeclampsia: a prospective multicenter study

LC Chappell, S Duckworth, PT Seed, M Griffin… - Circulation, 2013 - Am Heart Assoc
Background—Hypertensive disorders of pregnancy are a major contributor to death and
disability for pregnant women and their infants. The diagnosis of preeclampsia by using …

[HTML][HTML] Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data …

C Ovadia, PT Seed, A Sklavounos, V Geenes, C Di Ilio… - The Lancet, 2019 - thelancet.com
Background Intrahepatic cholestasis of pregnancy is associated with adverse perinatal
outcomes, but the association with the concentration of specific biochemical markers is …

Gender-linked hypertension in offspring of lard-fed pregnant rats

IY Khan, PD Taylor, V Dekou, PT Seed, L Lakasing… - …, 2003 - Am Heart Assoc
Epidemiological studies suggest an association between maternal nutrition and offspring
cardiovascular disease. We previously demonstrated endothelial dysfunction and abnormal …

A longitudinal study of biochemical variables in women at risk of preeclampsia

LC Chappell, PT Seed, A Briley, FJ Kelly… - American journal of …, 2002 - Elsevier
Objective: The purpose of this study was to characterize gestational profiles of biochemical
markers that are associated with preeclampsia in the blood of pregnant women in whom …