User profiles for "author:Paul Kirwan"

Paul D Kirwan

Trinity College Dublin, Ireland
Verified email at tcd.ie
Cited by 807

Tendinopathy

NL Millar, KG Silbernagel, K Thorborg… - Nature reviews Disease …, 2021 - nature.com
Tendinopathy describes a complex multifaceted pathology of the tendon, characterized by
pain, decline in function and reduced exercise tolerance. The most common overuse …

Frozen shoulder

NL Millar, A Meakins, F Struyf, E Willmore… - Nature reviews Disease …, 2022 - nature.com
Frozen shoulder is a common debilitating disorder characterized by shoulder pain and
progressive loss of shoulder movement. Frozen shoulder is frequently associated with other …

[HTML][HTML] The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review

S Docherty, R Harley, JJ McAuley, LAN Crowe… - BMC Sports Science …, 2022 - Springer
The physiological effects of physical exercise are ubiquitously reported as beneficial to the
cardiovascular and musculoskeletal systems. Exercise is widely promoted by medical …

'Have you seen what is on Facebook?'The use of social networking software by healthcare professions students

J White, P Kirwan, K Lai, J Walton, S Ross - BMJ open, 2013 - bmjopen.bmj.com
Objective The use of social networking software has become ubiquitous in our society. The
aim of this study was to explore the attitudes and experiences of healthcare professional …

Management of patellar tendinopathy: a systematic review and network meta-analysis of randomised studies

D Challoumas, C Pedret, M Biddle… - BMJ open sport & …, 2021 - bmjopensem.bmj.com
Objectives We performed a systematic review and network meta-analysis (NMA) of
randomised controlled trials (RCTs) to provide insights into the effectiveness of available …

Tumor necrosis factor α induces a model of preeclampsia in pregnant baboons (Papio hamadryas)

NS Sunderland, SE Thomson, SJ Heffernan, S Lim… - Cytokine, 2011 - Elsevier
Preeclampsia is a common disease of pregnancy characterised by maternal hypertension
and proteinuria. Abnormal placentation in early pregnancy and abnormal cytokine and anti …

Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia

MJ Menezes, Y Guo, J Zhang, LG Riley… - Human Molecular …, 2015 - academic.oup.com
Functional defects of the mitochondrial translation machinery, as a result of mutations in
nuclear-encoded genes, have been associated with combined oxidative phosphorylation …

Topical glyceryl trinitrate for the treatment of tendinopathies: a systematic review

D Challoumas, PD Kirwan, D Borysov… - British journal of sports …, 2019 - bjsm.bmj.com
Objective To produce a best evidence synthesis of the clinical effects of topical glyceryl
trinitrate (GTN) in the treatment of tendinopathies. Design A systematic review of published …

How does surgery compare to sham surgery or physiotherapy as a treatment for tendinopathy? A systematic review of randomised trials

D Challoumas, C Clifford, P Kirwan… - BMJ open sport & …, 2019 - bmjopensem.bmj.com
Purpose To assess the effectiveness of surgery on all tendinopathies by comparing it to no
treatment, sham surgery and exercise-based therapies for both mid-term (12 months) and …

ICON 2020—International Scientific Tendinopathy Symposium Consensus: a systematic review of outcome measures reported in clinical trials of Achilles tendinopathy

K Grävare Silbernagel, P Malliaras, RJ de Vos… - Sports Medicine, 2022 - Springer
Background Nine core domains for tendinopathy have been identified. For Achilles
tendinopathy there is large variation in outcome measures used, and how these fit into the …