Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach

C Menni, E Fauman, I Erte, JRB Perry… - Diabetes, 2013 - Am Diabetes Assoc
Using a nontargeted metabolomics approach of 447 fasting plasma metabolites, we
searched for novel molecular markers that arise before and after hyperglycemia in a large …

Metabolomic markers reveal novel pathways of ageing and early development in human populations

C Menni, G Kastenmüller, AK Petersen… - International journal …, 2013 - academic.oup.com
Background Human ageing is a complex, multifactorial process and early developmental
factors affect health outcomes in old age. Methods Metabolomic profiling on fasting blood …

Human CHN1 Mutations Hyperactivate α2-Chimaerin and Cause Duane's Retraction Syndrome

N Miyake, J Chilton, M Psatha, L Cheng, C Andrews… - Science, 2008 - science.org
Duane's retraction syndrome (DRS) is a complex congenital eye movement disorder caused
by aberrant innervation of the extraocular muscles by axons of brainstem motor neurons …

Circulating proteomic signatures of chronological age

C Menni, SJ Kiddle, M Mangino… - … Series A: Biomedical …, 2015 - academic.oup.com
To elucidate the proteomic features of aging in plasma, the subproteome targeted by the
SOMAscan assay was profiled in blood samples from 202 females from the TwinsUK cohort …

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate

C Menni, D Graham, G Kastenmüller, NHJ Alharbi… - …, 2015 - Am Heart Assoc
High blood pressure is a major contributor to the global burden of disease and discovering
novel causal pathways of blood pressure regulation has been challenging. We tested blood …

A longitudinal MRI study of muscle atrophy during lower leg immobilization following ankle fracture

M Psatha, Z Wu, FM Gammie… - Journal of Magnetic …, 2012 - Wiley Online Library
Purpose: To investigate MRI biomarkers of muscle atrophy during cast immobilization of the
lower leg. Materials and Methods: Eighteen patients (8 male, 10 female), who had one lower …

[HTML][HTML] Metabolomic study of carotid–femoral pulse-wave velocity in women

C Menni, M Mangino, M Cecelja, M Psatha… - Journal of …, 2015 - journals.lww.com
Objective: Carotid–femoral pulse-wave velocity (PWV) is a measure of aortic stiffness that is
strongly associated with increased risk of cardiovascular morbidity and mortality. The aim of …

[HTML][HTML] Nationwide survey in Greece about knowledge, risk perceptions, and preventive behaviors for COVID-19 during the general lockdown in April 2020

VA Mouchtouri, E Agathagelidou, K Kofonikolas… - International Journal of …, 2020 - mdpi.com
Background: The aim of this study was to investigate the knowledge, attitudes, and practices
of the Greek general population toward coronavirus disease 2019 (COVID-19) during the …

Targeting of calcium: calmodulin signals to the cytoskeleton by IQGAP1

MI Psatha, M Razi, A Koffer, SE Moss, DB Sacks… - Cell calcium, 2007 - Elsevier
Mast cells reorganize their actin cytoskeleton in response to cytosolic calcium signals while
in parallel secreting histamine and other inflammatory mediators. The effect of calcium on …

Stromal cell‐derived factor‐1 and hepatocyte growth factor guide axon projections to the extraocular muscles

O Lerner, D Davenport, P Patel… - Developmental …, 2010 - Wiley Online Library
Vertebrate eye movements depend on the co‐ordinated function of six extraocular muscles
that are innervated by the oculomotor, trochlear, and abducens nerves. Here, we show that …