Cellular hypoxia is the common final pathway of brain injury that occurs not just after
asphyxia, but also when cerebral perfusion is impaired directly (eg, embolic stroke) or …

Barometric pressure falls with increasing altitude and consequently there is a reduction in
the partial pressure of oxygen resulting in a hypoxic challenge to any individual ascending …

The treatment of cold injuries to the periphery has advanced substantially in the last 10
years and optimal outcomes are only likely to be achieved if a multidisciplinary team uses …

Acute altitude illnesses are potentially serious conditions that can affect otherwise fit
individuals who ascend too rapidly to altitude. They include high altitude headache, acute …

Background and Purpose—Inhibition of von Willebrand factor offers a novel approach to
prevention of stroke and myocardial ischemia but has not yet been demonstrated to show …

Non-freezing cold injury (NFCI) is the Cinderella of thermal injuries and is a clinical
syndrome that occurs when tissues are exposed to cold temperatures close to freezing point …

Frostbite is defined as the damage sustained by tissues while subject to temperatures below
their freezing point (typically− 0.55 C); in the broader sense it can include non-freezing cold …

Objective As inspired oxygen availability falls with ascent to altitude, some individuals
develop high‐altitude headache (HAH). We postulated that HAH results when hypoxia …

Background. Human leukocyte antigen (HLA) antibody-incompatible renal transplantation
has been increasingly performed since 2000 but with few data on the medium-term …

Exercise intolerance is an important comorbidity in patients with CKD. Anaerobic threshold
(AT) determines the upper limits of aerobic exercise and is a measure of cardiovascular …