Very‐low‐energy diets (VLEDs) and ketogenic low‐carbohydrate diets (KLCDs) are two
dietary strategies that have been associated with a suppression of appetite. However, the …

Obesity prevalence is generally higher in women than in men, and there is also a sex
difference in body fat distribution. Sex differences in obesity can be explained in part by the …

MIC-1/GDF15 is a stress response cytokine and a distant member of the transforming growth
factor beta (TGFb) superfamily, with no close relatives. It acts via a recently identified …

Anorexia and weight loss are part of the wasting syndrome of late-stage cancer, are a major
cause of morbidity and mortality in cancer, and are thought to be cytokine mediated …

Neuropeptide Y (NPY) is a downstream modulator of leptin action, possibly at the level of the
arcuate nucleus where NPY neurons are known to express both leptin receptors and Y2 …

Background & Aims Aerobic exercise reduces liver fat and visceral adipose tissue (VAT).
However, there is limited data from randomized trials to inform exercise programming …

Obesity and non-insulin-dependent diabetes are estimated to affect millions of people in the
world. This pathology is multifactorial, comprising complex interactions of genetic and …

Neuropepetide Y (NPY) is best known for its powerful stimulation of food intake and its
effects on reducing energy expenditure. However, the pathways involved and the regulatory …

Objective. The purpose of this study was to assess the effect of high intensity interval training
(HIIT) versus continuous aerobic exercise training (CONT) or placebo (PLA) on body …

Energy restriction induces physiological effects that hinder further weight loss. Thus,
deliberate periods of energy balance during weight loss interventions may attenuate these …