Technical noteDirectional variation in extensibility of human skin in vivo
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Bio-Engineering studies of the human skin—11
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Cited by (73)
Anisotropic mechanical characterization of human skin by in vivo multi-axial ring suction test
2023, Journal of the Mechanical Behavior of Biomedical MaterialsMultimodal investigation of a keloid scar by combining mechanical tests in vivo with diverse imaging techniques
2019, Journal of the Mechanical Behavior of Biomedical MaterialsThe mechanical behavior of skin: Structures and models for the finite element analysis
2017, Computers and StructuresCitation Excerpt :For more detailed information on tissue engineering of skin we refer to the reviews [136,63,134]. Since the work of Langer [3,137], it is understood that skin has preferential direction in the deformation consequence the collagen fiber layout [3,138,139,96]. However the complexity of the mechanical behavior is still under study through different types of ex-vivo and in vivo tests; e.g. mainly uniaxial, torsion, biaxial, multiaxial, indentation, bulge and wave propagation tests.
New regime in the mechanical behavior of skin: strain-softening occurring before strain-hardening
2017, Journal of the Mechanical Behavior of Biomedical MaterialsCitation Excerpt :Some grey areas or limitations however remain in both experimental approaches. Briefly, in vivo experiments based on techniques of uniaxial extension (Gibson et al., 1969; Manshot and Brakkee, 1986; Khatyr et al., 2004), torsion (Finlay, 1970; Sanders, 1973; Barbenel and Evans, 1977; Agache et al., 1980; Escoffier et al., 1989; Salter et al., 1993), suction (Alexander and Cook, 1977; Cua et al., 1990; Elsner et al., 1990; Diridollou et al., 2001; Delalleau et al., 2008; Gerhardt et al., 2009; Boyer et al., 2009; Krueger et al., 2011), wave propagation (Potts et al., 1983), indentation (Jachowicz et al., 2007; Pailler-Mattei et al., 2008; Boyer et al., 2012) or yet three-dimensional and multi-axial deformation techniques (Kvistedal and Nielsen, 2009; Flynn et al., 2011a) are generally restricted to linear properties of the living skin (except in Kvistedal and Nielsen, 2009; Flynn et al., 2011a), large deformations being excluded for ethical reasons. In addition, a major drawback of the in vivo measurements is that the different skin layers and the subcutaneous tissue cannot be characterized separately and that the skin thickness (required to calculate intrinsic mechanical parameters such as stress or modulus) is not easily determined (Agache et al., 1980; Cua et al., 1990; Elsner et al., 1990; Salter et al., 1993; Gerhardt et al., 2009; Boyer et al., 2009; Krueger et al., 2011).
A histological and mechanical analysis of the cardiac lead-tissue interface: Implications for lead extraction
2014, Acta BiomaterialiaCitation Excerpt :In planning these studies, the most clinically relevant mechanical aspect was determined to be circumferential tensile strength and failure load, as these properties dictate the ease of radial tissue disruption and ability to separate the surrounding fibrosis from the implant surface. We therefore calculated the circumferential mechanical properties of this tissue utilizing the experimental setup described in Fig. 4a, ignoring the likely variable elastic properties when stressed in other directions [22,37,38]. Not surprisingly, the collected tissue displayed mechanical properties consistent with other biomaterials.
Skin viscoelasticity studied in vitro by microprobe-based techniques
2014, Journal of Biomechanics