Table 2

RE-AIM framework and associated measures

DefinitionHow will this be measured?
ReachAbsolute number, proportion, and representativeness of individuals willing to participateRetention rate, dropout rate, representativeness of study sample (in regard to age, fitness level, SES)
EffectivenessImpact of an intervention on important outcomes, including potential negative effects, quality of life, and economic outcomesQuality of life, physical activity level, exercise knowledge, health status, use of healthcare services, aerobic capacity, lower extremity strength, exercise engagement, cardiovascular outcomes, adverse events
AdoptionAbsolute number, proportion, and representativeness of settings who are willing to initiate a programmeNumber of oncologists approached vs assisting with recruitment, characteristics of oncologists participating, adherence of participants
ImplementationSite fidelity to the intervention’s protocol: consistency of delivery as intended, time and cost of the interventionConsistency of intervention delivery compared with study protocol (measured through observation), adaptations needed, cost of delivery and cost-effectiveness
MaintenanceExtent that programme becomes part of routine organisational practices. At the individual level, long-term effects of a programme on outcomes after >6 months from last intervention sessionInstitutional-level
  • Programme continuation/institutionalisation at cancer centre

  • Sustained behaviour change/health outcomes of participants