Table 2

Samples, characteristics of interventions and outcome measures of the included studies

AuthorTendon affectedSample, mean/median age (range); % FSymptom durationInterventionsTreatment duration (follow-up)Adherence to treatmentOutcome measures
Gatz et al37Achilles.n=42, mean 49.5 years (21–73 years); 36%.2–100 months (mean 27.5 months).
  1.  Isotonic (eccentric) exercise (n=20).

  2.  Isotonic (eccentric) exercise + isometric exercise (n=22).

3 months
(0, 1 month, 3 months).
100% in first month and around 50% thereafter.
  1. VISA-A (pain, function).

  2. AOFAS (pain, function).

  3. Likert scale (clinical improvement with treatment).

  4. Roles and Maudsley score (clinical improvement with treatment).

  5. Tissue elasticity (shear wave elastography).

Clifford et al17Gluteal.n=30, mean 59.3 years (24–86 years); 90%.Mean 23 months.
  1.  Isometric exercise (n=15).

  2.  Isotonic exercise (n=15).

12 weeks
(0, 4 weeks, 12 weeks).
70% of isometric group and 58% of isotonic group completed 80% of treatment sessions.
  1. Tendon-specific: VISA-G (pain, function).

  2. NPRS 0–10 for pain.

  3. EQ-5D-5L (QoL).

  4. IPAQ-SF.

  5. GROC.

  6. PCS.

  7. HOOS.

Holden et al22Patellar.n=21, mean 26.5 years (18–40 years); 41%.10–84 months (mean 24 months).
  1. Isometric exercise (n=21).

  2. Dynamic (isotonic) exercise (n=21).

Same group performed both interventions.
Single session of each intervention.N/A.
  1. Pain intensity during SLDS (NRS 0–10).

  2. Pressure pain thresholds.

  3. Patellar tendon thickness (USS).

Vuvan et al34Wrist extensors.n=40, mean 48.5 years (?– ? years); 28%.2–8 months (mean 4 months).
  1. Wait and see (n=19).

  2. Isometric exercise (n=21).

8 weeks
(0–8 weeks).
87%.
  1. GROC.

  2. Tendon-specific: PRTEE (pain, disability).

  3. VAS 0–10 for pain.

  4. Pain-free grip strength (function).

  5. Thermal and pressure pain threshold (nervous system sensitisation).

Dupuis et al31Rotator cuff.n=43, mean 38.3 years (18–65 years); 44%.<6 weeks.Weeks 0–2:
  1. Isometric exercise (n=20).

  2. Ice therapy (n=23).


Weeks 3–6:
Both groups same isotonic exercise programme.
6 weeks
(0, 2 weeks, 6 weeks).
Weeks 0–2: exercise group 76% and cryotherapy group 80%.
Weeks 3–6: exercise group 40% and cryotherapy group 70%.
  1. USS to measure acromiohumeral distance.

  2. Strength (maximum force in shoulder abduction and external rotation).

  3. ROM.

  4. DASH (functional disability).

  5. Tendon-specific: WORC (QoL).

  6. BPI (pain 0–10).

Parle et al32Rotator cuff.n=20, mean 50 years (20–67 years); 65%.<12 weeks.
  1. Ice therapy (n=6).

  2. Isometric exercise (n=7).

  3. Ice therapy plus isometric exercise (n=7).

1 week
(0–1 week).
Unclear.
  1. VAS 0–10 for pain.

  2. DASH (functional disability).

  3. Strength (maximum force in shoulder flexion).

  4. Structural integrity (USS).

Rio et al35Patellar.n=29, mean 23 years (16–32 years); 7%.1–120 months (mean 35.8 months).
  1. Isometric exercise (n=13).

  2. Isotonic exercise (n=16).

4 weeks
(0, daily pre- exercise and postexercise, 4 weeks).
Unclear.
  1. Pain during the SLDS (NRS 0–10) preintervention and postintervention.

  2. Tendon-specific: VISA-P (pain, function).

Stasinopoulos and Stasinopoulos33Wrist extensors.n=34, mean 43 years ; 56%.>4 weeks (mean 6 months).
  1. Eccentric exercise (n=11).

  2. Eccentric-concentric exercise (n=12).

  3. Eccentric-concentric exercise + isometric exercise (n=11).

4 weeks
(0, 4 weeks, 8 weeks).
Unclear.
  1. VAS 0–10 for pain.

  2. Pain-free grip strength (function).

  3. VAS 0–10 for function.

van Ark et al36Patellar.n=29, mean 23 years (16–32 years); 7%.1–120 months (mean 35.8 months).
  1. Isometric exercise (n=13).

  2. Isotonic exercise (n=16).

4 weeks
(0–4 weeks).
Unclear.
  1. Pain during the SLDS (0–10).

  2. Tendon-specific: VISA-P (pain, function).

Rio et al20Patellar.n=6, median 27 years (18–40 years); 0%.Not stated.
  1. Isometric exercise (n=6).

  2. Isotonic exercise (n=6).

Same group performed both interventions.
Single session of each intervention (0–45 min).N/A.
  1. Pain during the SLDS (NRS 0–10).

  2. Strength (quadriceps MVIC).

  3. Measures of corticospinal excitability and inhibition.

  • The clinical parameters assessed by each questionnaire in the outcome measures are stated in brackets.

  • AOFAS, American Orthopaedic Foot and Ankle Score; BPI, Brief Pain Inventory; DASH, Disabilities of the Arm, Shoulder and Hand; EQ-5D-5L, EuroQoL 5 Dimensions 5 Level Index; GROC, Global Rating of Change; HOOS, Hip Disability and Osteoarthritis Outcome Score; IPAQ-SF, International Physical Activity Questionnaire-Short Form; MVIC, maximum voluntary isometric contraction; N/A, not applicable; NPRS, Numeric Pain Rating Scale; NRS, Numeric Rating Scale; PCS, Pain Catastrophising Scale; PRTEE, Patient-Rated Tennis Elbow Evaluation; QoL, quality of life; ROM, range of movement; SLDS, single leg decline squat; USS, ultrasound scan; VAS, Visual Analogue Scale; VISA-A, Victorian Institute of Sport Assessment-Achilles tendon; VISA-G, Victorian Institute of Sport Assessment-gluteal tendons; VISA-P, Victorian Institute of Sport Assessment-patellar tendon; ; WORC, Western Ontario Rotator Cuff Index.