Table 2

Association between concussion and the onset of MHS

	Univariate	Multivariate: adjusted for age	Multivariate: adjusted for family history	Multivariate: adjusted for age and family history
Association between a concussion reported on baseline and the onset of MHS during the subsequent 12 months
Distress	1.7 (0.9 to 3.4)	1.5 (0.8 to 3.0)	1.7 (0.9 to 3.4)	1.5 (0.8 to 3.0)
Anxiety/depression	1.1 (0.6 to 2.0)	1.1 (0.6 to 2.1)	1.1 (0.6 to 2.1)	1.1 (0.6 to 2.1)
Sleeping disturbance	1.0 (0.5 to 1.9)	1.0 (0.5 to 1.9)	1.0 (0.5 to 1.9)	1.0 (0.5 to 1.9)
Adverse alcohol use	2.0(1.1to3.5)	2.0 (1.1 to 3.5)	2.0(1.2to3.6)	2.0(1.1to3.6)
Eating disorder	1.1 (0.5 to 2.2)	1.1 (0.5 to 2.3)	1.1 (0.5 to 2.2)	1.1 (0.5 to 2.3)
Comorbidity	1.4 (0.8 to 2.6)	1.4 (0.8 to 2.5)	1.4 (0.8 to 2.6)	1.4 (0.8 to 2.5)
Association between the number of concussion recorded on baseline and the onset of MHS during the subsequent 12 months
Distress	1.5(1.0to2.1)	1.4 (0.9 to 2.0)	1.5(1.0to2.1)	1.4 (0.9 to 2.0)
Anxiety/depression	1.1 (0.8 to 1.6)	1.1 (0.8 to 1.6)	1.1 (0.8 to 1.6)	1.1 (0.8 to 1.6)
Sleeping disturbance	1.0 (0.7 to 1.5)	1.0 (0.7 to 1.5)	1.0 (0.7 to 1.5)	1.0 (0.7 to 1.5)
Adverse alcohol use	1.5 (1.1 to2.0)	1.5 (1.1 to2.0)	1.5 (1.1 to2.1)	1.5 (1.1 to2.1)
Eating disorder	1.1 (0.6 to 1.7)	1.1 (0.7 to 1.7)	1.0 (0.6 to 1.7)	1.1 (0.7 to 1.7)
Comorbidity	1.3 (0.8 to 1.9)	1.2 (0.8 to 1.9)	1.3 (0.9 to 1.9)	1.2 (0.8 to 1.9)