Lung function (FVC and FEV1), bronchial hyper-responsiveness (PD20met), VO2max, VEmax, TVmax, HRmax, RERmax, running time and running distance before and after the 5-month treatment of the four subjects
| Cases, male (♂) and female (♀) | FVC (L) (%pred) | FEV1(L) (%pred) | PD20met
(µmol) | VO2max
(mL/kg/min) | VEmax
(L/min) | TVmax
(L) | HRmax
(beats/min) | RERmax
(CO2/VO2) | Running time (min) | Running distance (m) | |
| 1 (♂) | Pre | 4.74 (95) | 4.40 (107) | 11.22 | 52.3 | 135 | 2.87 | 179 | 1.16 | 11.21 | 800 |
| Post | 5.14 (101) | 4.71 (113) | 12.54 | 53.2 | 138 | 3.07 | 183 | 1.24 | 12.49 | 1015 | |
| 2 (♀) | Pre* | 4.94 (139) | 3.71 (123) | 3.57 | 58.7 | 109 | 2.73 | 181 | 1.04 | 12.19 | 930 |
| Post | 5.12 (141) | 3.85 (125) | 1.68 | 49.8 | 105 | 2.23 | 182 | 1.23 | 12.28 | 965 | |
| 3 (♀) | Pre | 4.18 (92) | 3.89 (102) | 10.10 | 54.4 | 128 | 2.06 | 189 | 1.21 | 13.01 | 1043 |
| Post | 4.57 (100) | 4.11 (107) | 8.56 | 54.4 | 133 | 2.29 | 199 | 1.24 | 13.22 | 1096 | |
| 4 (♀) | Pre | 4.29 (94) | 4.18 (109) | >16.01 | 37.4 | 66 | 2.13 | 192 | 1.23 | 9.20 | 563 |
| Post | 4.59 (101) | 4.40 (115) | >16.01 | 37.0 | 80 | 2.24 | 197 | 1.26 | 10.01 | 641 |
*The physiological test results pretest are most likely due to equipment measure error.
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; HRmax, maximal heart rate; PD20met, provocation dose of methacholine causing 20% reduction in FEV1 from baseline; RERmax, maximal respiratory exchange ratio; TVmax, maximal tidal volume; VEmax, maximal minute ventilation; VO2max, maximal oxygen uptake.