Pulmonary function during placebo and salbutamol intervention in non-asthmatic, healthy individuals
| Baseline (n=36) | Placebo (n=36) | Salbutamol (n=36) | P values* | |
| Dynamic spirometry | ||||
| FEV1 (%) | 110±13 | 109±13 | 116±13 | <0.01 |
| FVC (%) | 117±12 | 116±12 | 118±12 | 0.06 |
| FEV1/FVC ratio | 0.80±0.06 | 0.80±0.06 | 0.84±0.06 | <0.01 |
| PEF (%) | 118±18 | 117±17 | 122±16 | 0.01 |
| Impulse oscillometry | ||||
| R5 (%) | 105±26 | 102±28 | 89±26 | <0.01 |
| R20 (%) | 113±25 | 112±27 | 96±24 | <0.01 |
| D5-20 | 13±13 | 12±13 | 12±12 | 0.87 |
Data are reported as mean percentage of predicted values with SD.
*Difference in effect from placebo and salbutamol intervention.
D5-20, part of the total resistance originating from the small conducting airways; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; PEF, peak expiratory flow; R5, total resistance in the conducting airways; R20, resistance in the large conducting airways.