Table 1

Biochemical variables and SCAT3 symptom metrics across all three experimental conditions

Variable	Heading		P values	Control		P values	Sham		P values
Variable	Pre	Post	P values	Pre	Post	P values	Pre	Post	P values
NF-L, pg/mL	14.5 (17.8)	16.1 (17.7)	0.004*	26.9 (41.9)	28.5 (44.4)	0.19†	10.2 (22.7)	10.7 (23.2)	0.02†
Tau, pg/mL	3.2 (1.7)	3.0 (1.3)	0.16†	4.0 (5.2)	2.5 (3.3)	0.14†	3.5 (4.0)	3.8 (2.6)	0.58†
Total no of symptoms	1.6 (1.9)	7.0 (6.9)	0.01*	1 (5)	0 (3)	0.04†	2.3 (2.2)	0.9 (1.7)	0.04*
Symptom severity	0 (4)	6 (14)	0.03*	1 (7)	0 (3)	0.04†	2 (6)	0 (2)	0.04†

*t-test; associated data are mean (SD).
†Wilcoxon signed-rank test; associated data are median (IQR).
NF-L, neurofilament light; SCAT3, Standardized Assessment of Concussion—3rd edition.