RCT |
Cohort studies |

1. Is a method of randomisation applied? |
1. Are study groups clearly defined? |

2. Is randomisation blinded? |
2. Is there any selection bias? |

3. Are the patients blinded? |
3. Is the exposure clearly defined? |

4. Is the therapist blinded? |
4. Is the outcome clearly defined? |

5. Is the outcome assessor blinded? |
5. Is the outcome assessment blinded? |

6. Are the groups comparable? |
6. Is the follow-up accurate? |

7. Is there an acceptable lost-to-follow-up? |
7. Is there an acceptable lost-to-follow-up? |

8. Is there an intention-to-treat? |
8. Are confounders described and/or eliminated? |

9. Are treatments comparable? |

RCT, randomised controlled trial.