Patient and study design characteristics
Study | Treatment period | Sample size | Female gender (%) | Age (year) | Tendinopathy | Minimum symptom duration (month) | Pain outcome | Follow-up (month) | |||
PRP | Control | PRP | Control | PRP | Control | ||||||
Behera et al13 | 2011–2011 | 15 | 10 | 80 | 50 | 38 | 37 | Lateral epicondylar | 3 | VAS | 12 |
de Jonge et al14 | 2008–2009 | 27 | 27 | 52 | 52 | 49 | 50 | Achilles | 2 | VISA-A | 12 |
Dragoo et al15 | 2009–2012 | A10 | 13 | 11 | 0 | 28 | 40 | Patellar | 1.5* | VAS | 6 |
Gautam et al16 | 2011–2012 | 15 | 15 | — | — | — | — | Lateral epicondylar | 6 | VAS | 6 |
Gosens et al17 | 2006–2008 | 51 | 49 | 52 | 56 | 47 | 47 | Lateral epicondylar | 6 | VAS | 24† |
Kesikburun et al18 | 2011–2011 | 20 | 20 | 65 | 70 | 46 | 51 | Rotator cuff | 3 | VAS | 12 |
Krogh et al‡19 | 2009–2010 | 20 | 20 | 55 | 55 | 48 | 45 | Lateral epicondylar | 3 | PRTEE | 3 |
Krogh et al‡40 | 2009–2010 | 20 | 20 | 55 | 45 | 48 | 44 | Lateral epicondylar | 3 | PRTEE | 3 |
Krogh et al20 | 2009–2011 | 12 | 12 | 42 | 50 | 47 | 52 | Achilles | 6 | VAS | 3 |
Lebiedziński et al21 | 2009–2011 | 64 | 56 | 47 | 74 | 47 | 54 | Lateral epicondylar | 1.5 | DASH | 12 |
Mishra et al22 | 2006–2011 | 112 | 113 | — | — | 48 | 47 | Lateral epicondylar | 3 | VAS | 6 |
Montalvan et al23 | 2010–2014 | 25 | 25 | 32 | 32 | 47 | 46 | Lateral epicondylar | —§ | VAS | 12 |
Palacio et al‡24 | 2012–2014 | 20 | 20 | — | — | 47 | 48 | Lateral epicondylar | — | PRTEE | 6¶ |
Palacio et al‡24 | 2012–2014 | 20 | 20 | — | — | 47 | 46 | Lateral epicondylar | — | PRTEE | 6¶ |
Rha et al25 | 2010–2011 | 20 | 19 | 55 | 58 | 52 | 54 | Rotator cuff | 6 | SPADI pain | 6 |
Shams et al26 | 2013–2015 | 20 | 20 | 50 | 45 | 52 | 50 | Rotator cuff | 3 | ASES | 6 |
Stenhouse et al27 | 2010–2012 | 15 | 13 | 47 | 62 | 53 | 48 | Lateral epicondylar | 6 | VAS | 6 |
Yadav et al28 | 2012–2014 | 30 | 30 | 67 | 77 | 37 | 37 | Lateral epicondylar | 1 | VAS | 3 |
‘—’ indicates missing data.
*Patients failed to respond to ≥6 weeks physical therapy; total symptom duration not reported.
†Data extracted through 12 months only for meta-analysis per systematic review methods (ie, data extraction at 3, 6 and 12 months); however, total symptom duration not reported.
‡Study includes same PRP group and different control groups. PRP group sample size adjusted in meta-analysis based on number of groups.
§Maximum symptom duration was 3 months.
¶Data extracted through 3 months only for meta-analysis due to implausible reported 6-month outcomes.
ASES, American Shoulder and Elbow Surgeons; DASH, Disabilities of the Arm, Shoulder and Hand score; PRP, platelet-rich plasma; PRTEE, Patient-Rated Tennis Elbow Evaluation; SPADI, Shoulder Pain and Disability Index; VAS, visual analogue scale; VISA-A, Victorian Institute of Sport Assessment-Achilles questionnaire.