Serum concentrations of muscular and renal biomarkers in patients and healthy controls on day 3 and in patients on day 24 after debut of rhabdomyolysis with discoloured urine
| p Difference: patients versus controls on day 3 | Control subjects on day 3, n=26 | Patients on day 3, n=8 | Patients on day 24, n=8 | p Difference: patients on day 3 versus day 24 | |
| CK U/L | p<0.0001 | 1553±2094 | 97 595±60 054 | 1994±4297 | p=0.01 |
| Myoglobin µg/L | p<0.0001 | 133±103 | 5223±2900 | 269±606 | p=0.003 |
| NGAL µg/L | p=0.05 | 198±59 | 246±54 | 186±40 | p=0.006 |
| CRP mg/L | p=0.03 | 4.1±3.9 | 13.3±14.2 | 2.8±2.3 | p=0.09 |
| Creatinine µmol/L | p=0.14 | 84±11 | 77±9 | 82±8 | p=0.12 |
| eGFR mL/min | p=0.14 | 114±14 | 123±10 | 117±11 | p=0.10 |
| Cystatin C mg/L | p=0.83 | 0.82±0.11 | 0.83±0.12 | 0.91±0.10 | p=0.07 |
Data are given as arithmetic mean±SD (range).
CK, creatine kinase, laboratory reference interval is 50–400 U/L (men 18–49 years); myoglobin, laboratory reference interval is 30–80 µg/L (men); NGAL, neutrophil gelatinase-associated lipocalin; CRP, C reactive protein, laboratory reference interval is 0–4 mg/L (both sexes); creatinine, laboratory reference interval is 60–105 µmol/L for men above 17 years; eGFR, estimated glomerular filtration rate, laboratory reference interval is 93–131 mL/min (men 17–24 years); cystatin C, laboratory reference interval is 0.51–1.05 mg/L (both sexes).