Selection of patients for screening of a genetic disorder
| Consider a genetic cause of the exertional rhabdomyolysis in case of ‘RHABDO’ | |
|---|---|
| R | Recurrent episodes of exertional rhabdomyolysis |
| H | HyperCKaemia persists 8 weeks after the event |
| A | Accustomed physical exercise |
| B | Blood CK>50×ULN (>10 000 ULN in female Caucasian patients) |
| D | Drugs/medication/supplements and other exogenous and endogenous factors cannot sufficiently explain the rhabdomyolysis severity |
| O | Other family members affected/Other exertional symptoms (cramps, myalgia) |
CK, creatine kinase; ULN, upper limit of normal.