Table 2

Pulmonary function, cardiorespiratory fitness variables and haemoglobin concentration before and 4–6 weeks after surgery

 Before surgeryAfter surgeryChange from baseline (95% CI)
Lobectomy
n=58
Pulmonectomy
n=12
Lobectomy
n=51
Pulmonectomy
n=8
Lobectomy
n=51
Pulmonectomy
n=8
FEV1, L2.4±0.82.6±0.72.0±0.61.7±0.3−0.4 (−0.5 to −0.3)−0.9 (−1.3 to −0.5)
DLCO, mmol/min/kPa6.7±2.17.2±2.35.5±1.64.8±1.2−1.3 (−1.6 to −1.0)−2.7 (−4.1 to −1.3)
V̇O2peak, mL/kg/min23.4±5.526.2±6.919.5±5.417.8±6.6−4.3 (−5.4 to −3.3)*−9.2 (−14.3 to −4.2)*
VEpeak, L/min59.8±18.067.3±16.047.4±14.044.4±16.6−11.3 (−14.8 to −7.8)*−21.6 (−32.8 to −10.3)*
Breathing reserve, %35.3±14.934.8±11.041.8±13.041.0±15.35.8 (3.0 to 8.6)*2.5 (−12.0 to 16.9)
SpO2peak, %93.4±4.190.3±6.793.3±3.392.9±3.4−0.6 (−0.2 to 1.5)0.9 (−3.3 to 1.5)
Oxygen pulse, mL/beat11.8±3.513.1±3.910.0±2.89.9±4.6−1.7 (−2.4 to −1.0)*−2.7 (−4.3 to −1.0)*
HRpeak,beat/min146.9±21.1152.4±21.3137.4±18.0127.5±18.6−9.5 (−12.8 to −6.1)*−24.9 (−40.2 to −9.5)*
Haemoglobin, g/dL14.7±1.614.2±1.813.9±1.313.6±2.4−0.7 (−1.1 to −0.2)*−1.1 (−2.4 to −0.3)
  • Data are presented as mean±SD; for pulmonary function, n=63 4–6 weeks after surgery.

  • *Change from baseline is significant at the 0.01 level

  • DLCO, carbon monoxide lung diffusion capacity; FEV1, forced expiratory volume after 1 s; HRpeak, peak heart rate; SpO2, oxygen saturation; VEpeak, peak minute ventilation; V̇O2peak, peak oxygen uptake.