RT Journal Article SR Electronic T1 Subjects with cardiovascular disease or high disease risk are more sedentary and less active than their healthy peers JF BMJ Open Sport & Exercise Medicine JO BMJ OPEN SP EX MED FD BMJ Publishing Group Ltd SP e000363 DO 10.1136/bmjsem-2018-000363 VO 4 IS 1 A1 Ville Vasankari A1 Pauliina Husu A1 Henri Vähä-Ypyä A1 Jaana Helena Suni A1 Kari Tokola A1 Katja Borodulin A1 Heini Wennman A1 Jari Halonen A1 Juha Hartikainen A1 Harri Sievänen A1 Tommi Vasankari YR 2018 UL http://bmjopensem.bmj.com/content/4/1/e000363.abstract AB Objectives We investigated differences in objectively measured sedentary behaviour (SB) and physical activity (PA) levels in subjects with cardiovascular disease (CVD) diagnosis or high CVD risk compared with healthy controls.Methods The present study includes a subsample (n=1398, Health 2011 Study) of participants, who attended health examinations and wore a triaxial accelerometer (≥4 days). Patients with CVD were identified and CVD risk was calculated for others using Framingham Risk Score (FRS). Participants were categorised into groups: FRS<10%; FRS=10%–30%; FRS>30%/CVD. Raw acceleration data were analysed with mean amplitude deviation (MAD) and angle for posture estimation (APE). MAD corresponding to intensity of PA was converted to metabolic equivalents (MET) and categorised to light (1.5–2.9 METs) and moderate to vigorous PA (MVPA≥3.0 METs). APE recognises SB and standing.Results Daily accumulated time of >30 s MVPA bouts was higher in FRS<10% group (46 min) than in FRS>30%/CVD group (29 min) (p<0.001). FRS>30%/CVD group were more sedentary, their mean daily number of >10 min SB bouts (13.2) was higher than in FRS <10% group (11.5) (p=0.002).Conclusion Number and accumulated times of SB and PA bouts differed between the CVD risk groups. Causative research is required to assess the importance of SB and PA in prevention and rehabilitation of CVDs.