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93 10-year prognosis of adolescent knee pain – a prospective population-based cohort study
  1. Michael Skovdal Rathleff1,2,3,
  2. Pernille Brøndum1,3,
  3. Eva Roos4,
  4. Line Bay Sørensen1,
  5. Jesper Bie Larsen1,
  6. Jens Lykkegaard Olesen3,
  7. Alison Chang1,5,
  8. Sinead Holden1,6
  1. 1Department of Health Science and Technology, Aalborg University, Denmark
  2. 2Department of Occupational Therapy and Physiotherapy, Department of Clinical Medicine, Aalborg University Hospital, Denmark
  3. 3Center for General Practice at Aalborg University, Denmark
  4. 4Center for Muscle and Joint Health, Department of Sports and Clinical Biomechanics, University of Southern Denmark, Denmark
  5. 5Department of Physical Therapy and Human Movement Sciences, Northwestern University Feinberg School of Medicine, USA
  6. 6UCD Clinical Research Centre, School of Medicine, University College Dublin, Ireland


Introduction Knee pain affects one in three adolescents. No studies have prospectively evaluated the long-term impact of knee pain in later life. The Adolescent Pain in Aalborg (APA 2011) cohort included a population-based sample of 504 adolescents aged 15–19 years with knee pain. This study aims to describe the preliminary findings from selected outcomes after 10-years.

Materials and Methods This population-based cohort study included the following outcomes at the 10 year follow-up: Knee injury and Osteoarthritis Outcome Score (KOOS), pain intensity, pain frequency, other pain locations, health-related quality of life, weekly sports participation, physical activity (International Physical Activity Questionnaire), sleep quality, healthcare consultations, diagnoses, and treatments or knee pain, pain-killer usage, and impact on the choice of job/career.

Results 53.8% of participants with knee pain at baseline have responded by 12/10/2022; (n=271, mean age=28.1±1.2 years, BMI=25.4±5.0 kg/m2, 71% women). Final results are expected in 2023. 38.0% experienced knee pain during the last week, with 33% reporting pain at least several times per week. Average KOOS Sport/recreation scores were 61±22, and KOOS QoL were 61±20 for those who continued to experience knee pain, and 86±15 and 84±15, respectively, for those recovered from knee pain. 60.0% with ongoing knee pain report difficulties sleeping.

Conclusion Preliminary findings from this first prospective population-based study examining the 10-year prognosis of knee pain from adolescence into adulthood indicate that knee pain persists after 10-years in nearly 40% of adolescents and is associated with very low KOOS scores compared to those recovered from knee pain.

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