Background
Severe mental illness, including schizophrenia, is among the most burdensome and costly illnesses worldwide.1 The clinical symptoms usually manifest in early adult life,2 and a substantial proportion of patients with schizophrenia experience persistent physical, functional and cognitive impairments.3 Psychotic symptoms are often effectively treated with antipsychotic medication, however, treatment is commonly accompanied by metabolic side effects. Patients treated with antipsychotic medication have a 4-fold higher prevalence of metabolic syndrome,4 and a 2–3 fold higher risk of cardiovascular disease compared with the general population,4 which contributes to a premature mortality rate of 15–20 years.5 Lifestyle factors, such as poor diet, smoking6 and physical inactivity,7 may contribute to the increased morbidity and mortality.
The Lancet Psychiatry Commission has pointed to physical activity as a key modifiable factor in protecting physical health in people with mental illness.8 Specifically, introducing exercise in the early stages of schizophrenia may be a sustainable solution in preventing or attenuating metabolic dysfunction associated with antipsychotic medication.8 9 Furthermore, exercise has been found efficacious in improving clinical symptoms, quality of life, global functioning and cognitive deficits,10–12 and early improvements in these outcomes may reduce the likelihood of enduring symptoms and functional disability.13 Moreover, patients in the early stages of schizophrenia are more physically active than patients with long-term schizophrenia,14 and thus potentially easier to engage in exercise. However, long-term maintenance of physical active behaviour is challenging.15 Replicable and scalable methods of delivering physical activity to patients with schizophrenia in the early stages of their disease in a format that is accessible, engaging and effective for a large number are warranted.16 Indeed, the WHO’s Mental Health Action Plan 2013–2030 calls for the provision of mental health services integrated in communities for service users and families.17 Accordingly, community-based group exercise may hold promise to support sustainable physical activity.18 Still, the initiation of community-based exercise in people with serious mental illness is not a simple step from intention to participation, but a non-linear slow phased transition with various challenges and setbacks at every phase.19
This study was conducted as a part of a project aiming to develop, evaluate and implement community-based exercise for young adults in antipsychotic treatment (ClinicalTrials.gov identifier: NCT05461885). Previously, we evaluated the impact and feasibility of a gym-based group exercise programme supervised by non-health professional exercise instructors for young adults in antipsychotic treatment (the COPUS trial).20 21 The results indicated that gym-based group exercise has the potential to support and promote personal recovery, which can be defined as ‘changing values, feelings, goals, abilities and roles in order to achieve a satisfactory, hopeful and productive way of life, with the possible limitation of the illness’.22 However, feasibility was challenged due to a lack of incentives and infrastructure to ensure consecutive recruitment from outpatient clinics to gym-based exercise in communities. Consequently, it was concluded that refinements in both the intervention itself and in its the delivery were warranted before initiating a large-scale, definitive trial.20 Also, community-based exercise programmes may be considered a complex intervention due to the properties of the intervention itself, that is, how the intervention produces change, and the interaction between the intervention and its context, that is, how the context affects implementation and outcomes. Hence, early considerations and continually revisiting core elements, that is, considering context, identifying key uncertainties, developing a programme theory and refining the intervention, are recommended throughout the research process when evaluating complex interventions.23 24 The current study aimed to explore the perspectives of various professional experts in relation to the development of community-based exercise for young adults with schizophrenia intended to promote long-term maintenance of physical activity.