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Effects of exercise training on physical and psychosocial health in children with chronic respiratory disease: a systematic review and meta-analysis
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  • Published on:
    Strong conclusions made on limited and inconsistent evidence
    • Thomas Radtke, Senior Researcher Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland
    • Other Contributors:
      • Sarah Nevitt, Research Associate

    To the Editor,

    We read with great interest the systematic review by Joschtel et al.1 on the effects exercise training on physical and psychological health in children with pediatric respiratory diseases such as asthma, bronchiectasis, bronchopulmonary dysplasia and cystic fibrosis (CF). Undoubtedly, the authors should be commended for their effort that they have put into this systematic review on an important research topic. However, we would like to take the opportunity to express some methodological concerns related to the CF studies included in this review.

    Joschtel et al.1 included studies on children, adolescents and young adults aged between 4 and 21 years and excluded those with a study population mean age of 21 years. These contradictory criteria have led to a false inclusion of one study 2 that included patients aged 12-40 years (although with a mean (SD) age of 19.5 (6.4) and 19.4 (5.3) for the intervention and control groups, respectively). Other studies 3 4, in which the mean age of the participants is <21 years were not considered for this review. Specifically, 3 out of 4 groups from the Kriemler et al. study 3 would qualify to be included in this review. Joschtel et al.1 did not publish a review protocol and therefore pre-specified inclusion and exclusion criteria cannot be verified.

    Joschtel et al.1 have conducted a meta-analysis on peak oxygen uptake (VO2peak), despite substantial heterogeneity of study characteristics (i.e., study...

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    Conflict of Interest:
    None declared.