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Preventing running-related injuries using evidence-based online advice: the design of a randomised-controlled trial
  1. Tryntsje Fokkema1,
  2. Robert-Jan de Vos2,
  3. John M van Ochten1,
  4. Jan AN Verhaar2,
  5. Irene S Davis3,
  6. Patrick JE Bindels1,
  7. Sita MA Bierma-Zeinstra1,
  8. Marienke van Middelkoop1
  1. 1 Department of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
  2. 2 Department of Orthopaedics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
  3. 3 Spaulding National Running Centre, Department of Physical Medicine and Rehabilitation, Harvard Medical School, Cambridge, Massachusetts, USA
  1. Correspondence to Tryntsje Fokkema; t.fokkema{at}


Introduction Running-related injuries (RRIs) are frequent and can lead to cessation of health promoting activities. Several risk factors for RRIs have been identified. However, no successful injury prevention programme has been developed so far. Therefore, the aim of the present study is to investigate the effect of an evidence-based online injury prevention programme on the number of RRIs.

Methods and analysis The INSPIRE trial is a randomised-controlled trial with a 3-month follow-up. Both novice and more experienced runners, aged 18 years and older, who register for a running event (distances 5 km up to 42.195 km) will be asked to participate in this study. After completing the baseline questionnaire, participants will be randomised into either the intervention group or control group. Participants in the intervention group will get access to the online injury prevention programme. This prevention programme consists of information on evidence-based risk factors and advices to reduce the injury risk. The primary outcome measure is the number of self-reported RRIs in the time frame between registration for a running event and 1 month after the running event. Secondary outcome measures include the running days missed due to injuries, absence of work or school due to injuries, and the injury location.

Ethics and dissemination An exemption for a comprehensive application is obtained by the Medical Ethical Committee of the Erasmus University Medical Centre Rotterdam, Netherlands. The results of the study will be published in peer-reviewed journals and presented on international congresses.

Trial registration number NTR5998. Pre-results

  • Running injuries
  • Prevention
  • RRI
  • Injury prevention program

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  • Contributors R-JdV and MvM wrote the medical ethical approval application. TF wrote the article, which is based on the funding application written by MvM and R-JdV. The trial was coordinated by MvM.

  • Funding This work was supported by the Netherlands Organisation for Health Research and Development (ZonMW), grant number 536001001.

  • Competing interests None declared.

  • Ethics approval Medical Ethical Committee of the Erasmus University Medical Center Rotterdam, Netherlands.

  • Provenance and peer review Not commissioned; externally peer reviewed.