In vivo measurements of muscle specific tension in adults and children
TD O'Brien, ND Reeves, V Baltzopoulos… - Experimental …, 2010 - Wiley Online Library
To better understand the effects of pubertal maturation on the contractile properties of
skeletal muscle in vivo, the present study investigated whether there are any differences in …
skeletal muscle in vivo, the present study investigated whether there are any differences in …
[HTML][HTML] Human skeletal muscle possesses an epigenetic memory of hypertrophy
It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters
with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000 …
with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000 …
Mechanical properties of the patellar tendon in adults and children
TD O'Brien, ND Reeves, V Baltzopoulos… - Journal of …, 2010 - Elsevier
It is not currently known how the mechanical properties of human tendons change with
maturation in the two sexes. To address this, the stiffness and Young's modulus of the …
maturation in the two sexes. To address this, the stiffness and Young's modulus of the …
[HTML][HTML] Stretching interventions in children with cerebral palsy: why are they ineffective in improving muscle function and how can we better their outcome?
BM Kalkman, L Bar-On, TD O'Brien… - Frontiers in …, 2020 - frontiersin.org
Hyper-resistance at the joint is one of the most common symptoms in children with cerebral
palsy (CP). Alterations to the structure and mechanical properties of the musculoskeletal …
palsy (CP). Alterations to the structure and mechanical properties of the musculoskeletal …
Muscle–tendon structure and dimensions in adults and children
TD O'Brien, ND Reeves, V Baltzopoulos… - Journal of …, 2010 - Wiley Online Library
Muscle performance is closely related to the architecture and dimensions of the muscle–
tendon unit and the effect of maturation on these architectural characteristics in humans is …
tendon unit and the effect of maturation on these architectural characteristics in humans is …
Strong relationships exist between muscle volume, joint power and whole‐body external mechanical power in adults and children
TD O'Brien, ND Reeves, V Baltzopoulos… - Experimental …, 2009 - Wiley Online Library
The present study investigated whether differences between adults and children in
mechanical power during single‐joint knee extension tasks and the complex multijoint task …
mechanical power during single‐joint knee extension tasks and the complex multijoint task …
Systematic review of physical activity and exercise interventions to improve health, fitness and well-being of children and young people who use wheelchairs
TD O'Brien, J Noyes, LH Spencer… - BMJ open sport & …, 2016 - bmjopensem.bmj.com
Aim To perform a systematic review establishing the current evidence base for physical
activity and exercise interventions that promote health, fitness and well-being, rather than …
activity and exercise interventions that promote health, fitness and well-being, rather than …
Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients
AB Lemmey, TJ Wilkinson, RJ Clayton, F Sheikh… - …, 2016 - academic.oup.com
Objective. RA typically features rheumatoid cachexia [loss of muscle mass (MM) and
excessive total fat mass (TFM), especially trunk FM], which contributes to physical disability …
excessive total fat mass (TFM), especially trunk FM], which contributes to physical disability …
Association between somatosensory, visual and vestibular contributions to postural control, reactive balance capacity and healthy ageing in older women
We investigated the biological systems involved in maintaining equilibrium during unstable
and perturbed conditions in 39 healthy older women and estimated the annual difference in …
and perturbed conditions in 39 healthy older women and estimated the annual difference in …
Can creatine supplementation improve body composition and objective physical function in rheumatoid arthritis patients? A randomized controlled trial
TJ Wilkinson, AB Lemmey, JG Jones… - Arthritis care & …, 2016 - Wiley Online Library
Objective Rheumatoid cachexia (muscle wasting) in rheumatoid arthritis (RA) patients
contributes to substantial reductions in strength and impaired physical function. The …
contributes to substantial reductions in strength and impaired physical function. The …