Could muscle deformity in children with spastic cerebral palsy be related to an impairment of muscle growth and altered adaptation?

M Gough, AP Shortland - Developmental Medicine & Child …, 2012 - Wiley Online Library
Skeletal muscle deformity is common in children with spastic cerebral palsy (CP), but the
underlying mechanisms are unclear. This review explores some possible factors which may …

Muscle deficits in cerebral palsy and early loss of mobility: can we learn something from our elders?

A Shortland - Developmental Medicine & Child Neurology, 2009 - Wiley Online Library
Ambulant young people with cerebral palsy (CP) have reduced muscle volumes in their
lower limbs (as low as 50% of their weight‐matched typically‐developing peers). Yet, they …

The morphology of the medial gastrocnemius in typically developing children and children with spastic hemiplegic cerebral palsy

R Malaiya, AE McNee, NR Fry, LC Eve… - … of electromyography and …, 2007 - Elsevier
We collected 3D ultrasound images of the medial gastrocnemius muscle belly (MG) in 16
children with spastic hemiplegic cerebral palsy (SHCP)(mean age: 7.8 years; range: 4–12) …

Architecture of the medial gastrocnemius in children with spastic diplegia

AP Shortland, CA Harris, M Gough… - … medicine and child …, 2002 - cambridge.org
Ultrasound images were obtained of the medial gastrocnemius at different ankle joint
positions with the knee extended. Fascicle length and deep fascicle angle were measured in …

Increases in muscle volume after plantarflexor strength training in children with spastic cerebral palsy

AE McNee, M Gough, MC Morrissey… - … Medicine & Child …, 2009 - Wiley Online Library
Children with spastic cerebral palsy (CP) have small, weak muscles. However, change in
muscle size due to resistance training in this group is unknown. We investigated the effect of …

Lower limb muscle volumes in bilateral spastic cerebral palsy

JJ Noble, NR Fry, AP Lewis, SF Keevil, M Gough… - Brain and …, 2014 - Elsevier
Aim: Muscle weakness is a feature of individuals with spastic cerebral palsy (SCP) but there
are few reports in the literature of muscle volume in this group. This study compares muscle …

European consensus on the concepts and measurement of the pathophysiological neuromuscular responses to passive muscle stretch

JC van den Noort, L Bar‐On… - European journal of …, 2017 - Wiley Online Library
Background and purpose To support clinical decision‐making in central neurological
disorders, a physical examination is used to assess responses to passive muscle stretch …

Short-term outcome of multilevel surgical intervention in spastic diplegic cerebral palsy compared with the natural history

M Gough, LC Eve, RO Robinson… - … medicine and child …, 2004 - cambridge.org
Outcome in 24 ambulant children with spastic diplegic cerebral palsy, in whom multilevel
surgical intervention was recommended following gait analysis, is reviewed. Twelve children …

Changes in the volume and length of the medial gastrocnemius after surgical recession in children with spastic diplegic cerebral palsy

NR Fry, M Gough, AE McNee… - Journal of Pediatric …, 2007 - journals.lww.com
Background: Morphology is an important determinant of muscle force and power generation.
Children with spastic diplegic cerebral palsy (SDCP) have reduced muscular strength, which …

Sodium channel protein expression enhances the invasiveness of rat and human prostate cancer cells

P Smith, NP Rhodes, AP Shortland, SP Fraser… - FEBS …, 1998 - Wiley Online Library
Expression of Na+ channel protein was analysed in established cell lines of rat and human
prostatic carcinoma origin by flow cytometry using a fluorescein‐labelled polyclonal …