Effects of Exercise-Based Interventions on Neonatal Outcomes: A Meta-Analysis of Randomized Controlled Trials

Am J Health Promot. 2016 Mar;30(4):214-23. doi: 10.1177/0890117116639569.

Abstract

Objective: The aim of this study was to conduct a systematic review and meta-analysis of randomized controlled clinical trials (RCTs) assessing the influence of physical exercise interventions during pregnancy on some neonatal outcomes.

Data source: Key words were used to conduct a computerized search in six databases: Cochrane Library Plus, Science Direct, EMBASE, PubMed, Web of Science, and ClinicalTrials.gov.

Study inclusion and exclusion criteria: RCTs that included an exercise program for healthy pregnant women who were sedentary or had low levels of physical activity were selected.

Data extraction: Two independent reviewers extracted data and assessed the quality of the studies included. Of 4296 articles retrieved, 14 RCTs (3044 pregnant women) met the inclusion criteria.

Data synthesis: Pooled effect sizes (ESs) were calculated using a fixed model.

Results: Overall, physical exercise programs during pregnancy produced a small reduction in neonatal birth weight (ES = -.10; p = .04). The Apgar score at 1 minute was also weakly increased with combined exercise (aerobic, strength, and flexibility) (ES = .09; p = .048) and no differences between groups were observed in gestational age at delivery and Apgar score at 5 minutes.

Conclusion: Structured physical exercise programs during pregnancy appear to be safe for the neonate, mainly favoring a lower birth weight within normal range. However, more studies are needed to establish recommendations.

Keywords: Apgar score; birth weight; exercise; gestational age; physical activity; pregnancy.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Apgar Score
  • Exercise Therapy* / methods
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Pregnancy Outcome
  • Pregnancy*
  • Randomized Controlled Trials as Topic
  • Sedentary Behavior