Selected associations between physical activity (ie, participation in the 8-week exercise programmes described in the text) and biomolecular, vascular haemodynamic, and clinical parameters related to CVD risk (see text for details).
| Physical activity | ||
|---|---|---|
| IPAQ (MET-min/week) | ||
| r | p Value | |
| Biomolecular | ||
| MMP-9 expression | −0.502 | <0.001 |
| CD36 expression | 0.343 | 0.013 |
| ABCA1 expression | 0.356 | 0.010 |
| Vascular haemodynamic | ||
| Systolic BP (mm Hg) | −0.371 | 0.004 |
| Diastolic BP (mm Hg) | −0.475 | <0.001 |
| Mean arterial pressure (mm Hg) | −0.459 | <0.001 |
| Central systolic BP (mm Hg) | −0.323 | 0.013 |
| Central diastolic BP (mm Hg) | −0.327 | 0.011 |
| AIx at HR 75 bpm (%) | −0.293 | 0.029 |
| MAP-adjusted carotid-femoral PWV (m/s) | −0.340 | 0.015 |
| Biomolecular | ||
| MMP-9 expression | ||
| r | p Value | |
| Vascular haemodynamic | ||
| Systolic BP (mm Hg) | 0.420 | 0.014 |
| Pulse pressure (mm Hg) | 0.354 | 0.003 |
| AIx at HR 75 bpm (%) | 0.282 | 0.050 |
| Clinical | ||
| Total cholesterol (mmol/L) | 0.398 | 0.015 |
| LDL-cholesterol (mmol/L) | 0.363 | 0.027 |
| ABCA1 expression | ||
| r | p | |
| Glucose (mmol/L) | −0.329 | 0.028 |
Bivariate correlation analyses were carried out using Pearson's method, with ‘Δ changes’ (ie, differences between measurements taken pre-exercise at weeks 0 and 8 of the intervention) as the source data for these analyses. (Please note that parameters that did not exhibit significant correlations were omitted from this table.)
ABCA1, ATP-Binding Cassette protein A1; AIx, Augmentation Index; BP, blood pressure; CVD, cardiovascular disease; HR, heart rate; LDL, low-density lipoprotein; MAP, mean arterial pressure; MMP-9, matrix metalloproteinase-9; PWV, pulse wave velocity.