Study 1 (n=22) | Study 2(n=65) | Study 3 (n=11) | ||
---|---|---|---|---|
Adherent gp; n=32 | Non-adherent gp; n=33 | |||
Physical activity | ||||
Number of additional steps/week | 30 000 | 8684±236*** | NA | 3486±469* |
Number of/duration of sessions/week | 3×45 min | 2×34±3 min | NA | 2×35 min |
METs per session | 4.74 (or 14.22/week) | 3.58±0.06 (or 7.16/week) | NA | 2.33±0.10 (or 4.66/week) |
Δ IPAQ MET-min/week | 540±0 | 296±29** | −51±37 | 98±142 |
Anthropometric | ||||
Δ Mass (kg) | −0.9±0.3*** | 0.2±1.3 | 0±1.1 | −0.5±0.4 |
Δ BMI (kg/m2) | −0.4±0.1** | 0±0.6 | −0.3±0.4 | −0.3±0.1(*) |
Δ Waist circumference (cm) | −5.5±1.1*** | −0.8±2.6 | −0.8±1.9 | 0±0.9 |
Biomolecular | ||||
CD36 (cf. week 0) | 1.90±0.50* | 1.88±0.21* | 1.15±0.26 | 1.91±0.72 |
ABCA1 (cf. week 0) | 1.95±0.31* | 2.78±0.45* | 1.47±0.46 | 1.37±0.40 |
MMP-9 (cf. week 0) | 0.52±0.16** | 0.69±0.08*** | 1.14±0.10 | 0.64±0.21(*) |
Vascular haemodynamic | ||||
Δ Systolic BP (mm Hg) | −6.1±2.6* | −6.0±9.0** | −1.0±5.0 | 4.8±2.5 |
Δ Diastolic BP (mm Hg) | −0.6±1.8 | −3.0±6.0** | 1.0±4.0 | −4.1±1.3* |
Δ Pulse pressure (mm Hg) | −5.5±2.4* | −3.0±9.0 | −2.0±6.0 | 5.2±3.1 |
Δ Mean arterial pressure (mm Hg) | −2.5±1.7(*) | −4.0±6.0** | 0±4.0 | −2.6±1.7* |
Δ Central systolic BP (mm Hg) | (–) | −5.0±7.0** | 0±5.0 | 4.9±2.2 |
Δ Central diastolic BP (mm Hg) | (–) | −3.0±7.0** | 2.0±3.0 | −0.6±1.3 |
Δ Central pulse pressure (mm Hg) | (–) | −2.0±7.0 | −1.0±5.0 | 5.4±2.8 |
Δ AIx at HR 75 bpm (%) | (–) | −4.0±6.0** | 1.0±7.0 | −3.0±0.4* |
Δ MAP-adjusted carotid-femoral PWV (m/s) | (–) | 0.1±0.4 | 0.1±0.4 | −0.3±0.2(*) |
Δ HR (bpm) | −2.2±2.9 | −1.0±8.0 | 2.0±9.0 | −6.8±2.9(*) |
Clinical | ||||
Δ Triglycerides (mmol/L) | 0.1±0.1 | −0.1±0.4 | −0.2±0.6 | −0.1±0.1 |
Δ Total cholesterol (mmol/L) | 0.3±0.4 | −0.1±0.5 | 0.1±0.4 | −0.4±0.1** |
Δ HDL-cholesterol (mmol/L) | 0.1±0.1 | 0.1±0.3 | 0±0.3 | −0.1±0 |
Δ LDL-cholesterol (mmol/L) | −0.1±0.2 | −0.1±0.9 | 0.1±0.5 | −0.4±0.1* |
Δ Glucose (mmol/L) | −0.1±0.1 | 0.1±0.5 | 0±0.2 | −0.3±0.2 |
Δ Insulin (pmol/L) | −16.2±9.6(*) | −0.2±4.1 | 0.3±4.6 | −2.8±2.3 |
Δ HOMA-IR (mmol/L, μU/mL) | −0.6±0.3* | 0±0.1 | 0±0.1 | 0.4±0.2 |
ABCA1, ATP-Binding Cassette protein A1; AIx, Augmentation Index; BMI, body mass index; BP, blood pressure; CD36, cluster of differentiation isoform-36; HDL, high-density lipoprotein; HOMA,homoeostatic model assessment; HR, heart rate; IPAQ,International Physical Activity Questionnaire; LDL,low-density lipoprotein; MAP, mean arterial pressure; MMP-9, matrix metalloproteinase-9; NA, not available; PWV, pulse wave velocity.